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DESCRIPTION. PLAVIX (clopidogrel bisulfate) is an inhibitor of ADP-induced platelet aggregation acting by direct inhibition of adenosine diphosphate (ADP) ...

The effectiveness of Plavix is dependent on its activation to an active metabolite by the cytochrome P450 (CYP) system, principally CYP2C19 [see Warnings and ...

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Mar 12, 2010 ... Boxed warning added regarding reduced effectiveness of Plavix in poor metabolizers.

Oct 27, 2010 ... The U.S. Food and Drug Administration (FDA) is reminding the public that it continues to warn against the concomitant use of Plavix ...

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May 20, 2012 ... Generic versions of blood-thinning medication - Plavix (clopidogrel bisulfate) - have been approved by the FDA (Food and Drug Administration) ...

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